This Course is about the burden of Non-Communicable Disease (NCDs), risk factors, NCD epidemiology, NCD and the Law and covering other dimensions of NCD globally, in the Pacific and in Fiji. It will review and discuss the Pacific NCD framework and targets, the social determinants and economic burden for NCDs and the causal webs. PCP810 will also discuss the components of NCDs strategies and plans with the different populations and high risk approaches in prioritizing health issues. Cardiovascular diseases, diabetes, cancers and chronic respiratory diseases are the four main NCDs contributing to the global burden of diseases. Countries around the world including the Pacific Island nations have acknowledged that the burden of NCDs constitutes one of the major challenges for development in this century. It is a vicious cycle whereby NCDs and their risk factors worsen poverty, while poverty contributes to rising rates of NCDs. Current NCD burden is high in Pacific Island countries and areas placing an enormous burden on individuals, families and communities as well as national health systems. As such Pacific Islands Forum Leaders and the Pacific Ministers of Health meeting have declared the Pacific being in a NCD crisis in 2011. The political declaration of the high level meeting of the United Nations General Assembly on the prevention and control of NCDs urged relevant international organisations to continue to provide technical assistance and capacity building in the areas of NCD prevention and control.NCDs diseases are preventable. The World Health Organization estimated that up to eighty per cent of diseases could be prevented by eliminating four shared risk factors of tobacco use, unhealthy diet, physical inactivity and harmful use of alcohol. Exposure to these risk factors could be reduced through collective multisectoral and health systems action by governments and key stakeholders